Model Overview

Our Human Proximal Tubule Kidney-Chip recreates true-to-life functions of the proximal tubule and is available in a co-culture configuration that incorporates relevant extracellular matrix (ECM) interactions and an epithelial-endothelial cell interface, along with relevant cyto-architecture and physiological flow.

 
 
 
 

 

Applications


Our Proximal Tubule Kidney-Chip demonstrates in vivo-relevant responses to known and tool compounds at clinically relevant concentrations and through the appropriate mechanisms of action.

General Toxicity • Mechanistic Toxicity • Drug Transport (coming soon)

 

 
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Kidney Bio-Kit

Our Proximal Tubule Kidney-Chip is currently available as a kit that includes Organ-Chips, cells, reagents, training, and support from our team. For more information about kit options and pricing, contact us below.

 
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Kidney Services

We offer services run on our Proximal Tubule Kidney-Chip to deliver clinically-relevant, decision-worthy insights. Our experienced services team is ready to design and execute studies with your desired endpoints in mind.

 

Resources

Publications

 
 
 

Protocols

Protocols developed by our experts guide the process of Kidney-Chip culture and analysis.