Model Overview

Our Intestine-Chips recreate true-to-life functions of the small intestine and colon. The fluidic channels of our Intestine-Chip make it possible to culture intestinal cells along with commensal bacteria, recreating a human-relevant microbiome. Our Intestine-Chips can be configured with primary, Caco-2, or induced pluripotent stem cells (iPSCs) derived from patients with diseases of the intestine.

It features human intestinal epithelial cells and intestinal-specific endothelial cells and has been used in a range of applications, including in the study of ulcerative colitis, IBS, Crohn’s, and viral infection.

 
 
 
 

 
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Intestine Services

We offer services run on our Intestine-Chip (Caco-2) to deliver clinically-relevant, decision-worthy insights. Our experienced services team is ready to design and execute studies with your desired endpoints in mind.

 

Resources

Publications